Blood pressure patients, check your bottles now. I have confirmed a new recall of the combination drug Ziac, used for hypertension. Some bottles contain trace contamination with a cholesterol medicine. The risk is low, but the guidance is clear. Verify your medication today and talk to your care team before making any changes.
What was recalled today
Glenmark has initiated a voluntary recall of Ziac, which contains bisoprolol fumarate and hydrochlorothiazide. Testing found tiny amounts of ezetimibe, a cholesterol drug, in certain bottles. The Food and Drug Administration has classified this as a Class III recall. That means use or exposure is not likely to cause adverse health effects.
The affected count sizes include 30, 100, and 500 tablets. The National Drug Codes are 68462-878-30, 68462-878-01, and 68462-878-05. The recalled lots carry expiration dates from November 2025 through May 2026. About 11,100 bottles are involved nationwide.
Check your Ziac bottle for NDC 68462-878-30, 68462-878-01, or 68462-878-05, and expirations from Nov 2025 through May 2026.
Ezetimibe is not a blood pressure medicine. It lowers LDL cholesterol by blocking absorption in the gut. At trace levels, it is not expected to change blood pressure, heart rate, or electrolytes. Still, any cross contamination is a quality failure that must be addressed.
What patients should do now
Do not stop your blood pressure medicine on your own. An abrupt stop can raise blood pressure and strain the heart. Here is the safest path forward.
- Check the NDC and expiration date on your bottle. Look at the pharmacy label and the manufacturer panel.
- If your bottle matches the affected NDCs and dates, call your pharmacy or prescriber today.
- Ask for a replacement supply that is not part of the recall.
- If you have symptoms that worry you, such as chest pain, severe dizziness, or fainting, seek urgent care.
Do not skip doses without medical advice. Stopping beta blockers or diuretics suddenly can cause rebound symptoms and spikes in blood pressure.
If your bottle does not match the listed NDCs or dates, continue your routine dosing. Keep your next refill on schedule. If you are unsure, your pharmacist can confirm with a quick lot check.
Snap a clear photo of your bottle label, including NDC, lot, and expiration, before you call. It speeds up replacement.
What this means for your health
Ziac combines a beta blocker and a diuretic. It lowers heart rate, relaxes vessels, and removes extra fluid. The contaminant, ezetimibe, acts on cholesterol absorption in the intestines. The FDA says this recall is unlikely to harm patients. Based on what I have reviewed, side effects from trace ezetimibe in this setting are not expected.
The bigger issue is confidence in your pill bottle. Hypertension control is fragile when doses are missed. Stay on therapy, and get a clean supply if your lot is involved. Monitor your blood pressure at home this week. Keep a simple log, morning and evening, until your replacement arrives.
Why this recall matters now
This event follows other quality issues in 2025. In October, prazosin was recalled due to a nitrosamine impurity. Earlier in the year, some metoprolol extended release lots failed dissolution testing. Different problems, same theme, manufacturing and oversight gaps that can touch common heart medicines.
Pharmacies are already triaging stock and contacting patients. Clinicians can prevent gaps in care by approving short bridge fills, offering equivalent alternatives, and giving clear instructions. Patients deserve quick, calm answers. A same day replacement avoids unnecessary spikes in blood pressure and anxiety.
Continuity is the goal. Your care team should help you switch lots or switch drugs without missing doses. If you use mail order, alert them now and request an unaffected lot. If supply is tight, your prescriber can choose a therapeutically similar option and send the prescription today.
Frequently Asked Questions
What exactly was found in Ziac?
Tiny amounts of ezetimibe, a cholesterol drug, were detected in certain bottles. This was due to cross contamination during manufacturing.
Is this dangerous?
The FDA classified it as Class III. That means it is not likely to cause harm. Even so, affected bottles should be replaced.
Should I stop taking my pills?
No. Do not stop without talking to your doctor or pharmacist. Stopping can raise blood pressure and cause symptoms.
How do I know if my bottle is part of the recall?
Check the NDC and expiration date. Affected NDCs are 68462-878-30, 68462-878-01, and 68462-878-05. Expirations run from Nov 2025 through May 2026.
What will the pharmacy do?
They can verify your lot and replace the medication with an unaffected batch. If needed, they will contact your prescriber for a new script.
In breaking news like this, speed and steadiness save health. Today’s Ziac recall carries low medical risk, but it deserves your attention. Check your label, call your pharmacy, and keep your blood pressure controlled. Your next safe dose, on time, is the priority.
